Knowing this, it will not come as a surprise that Linoleic acid has a central role in the structure and function of stratum corneum permeability, aka healthy skin barrier. It is the most abundant fatty acid in the epidermis and it serves as a structural precursor for important skin lipids called ceramides. Even better, if the formula also contains Ceramide 2.Īs for linoleic acid and the skin, LA is a really important little guy found naturally in our skin. So the bottom line is: if barrier repair is something that you are interested in, the skin surface lipids of L22 can definitely be worth a try. After 1 hour, they performed similarly both for barrier repair and skin hydration, but after 2 weeks of use and a 1 week regression period, L22 showed significantly better results. Skin hydration was measured 4 hours after application and again, the L22 + Ceramide 2 combination performed the best followed by L22 alone.Īnother study compared 3% L22 with 3% petrolatum (the gold standard occlusive agent).
60 minutes after the application, barrier recovery was by far the best by the L22 + Ceramide 2 (0.1%) combination, followed by L22 alone, and then by Olive + Ceramide 2 and Olive alone. It compared 3% of L22 with 3% of olive oil or 3% of caprylic/capric triglyceride alone or combined with Ceramide 2 in a vehicle. So the main skill of L22 is barrier repair and skin hydration and the manufacturer did several double-blind, vehicle-controlled studies to show it really works. It comes to the formula with Squalene, Phytosteryl Macadamiate (botanical sourced version of cholesteryl ester) and Phytosterols (botanical version of cholesterol) in the ratios found in young, healthy adult skin. So Jojoba Oil/Macadamia Seed Oil Esters is a jojoba and macadamia oil-derived ingredient that contains fatty acids, triglycerides, and wax esters. Lauryl PEG-9 Polydimethylsiloxyethyl Dimethiconeĭimethicone/Vinyl Dimethicone Crosspolymer Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
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